Allele/Variant

Mmp28tm1Mani

Species
Mus musculus
Symbol
Mmp28tm1Mani
Category
allele
Allele of gene
Mmp28
Transgenic Constructs
None
Synonyms
  • Epilysin-
Description
Exons 4-7 and the coding portion of exon 8 were replaced with a neomycin selection cassette. This mutation was predicted to be a null allele because the remaining exons 1-3 only encode the proregion of the protein product. Protein product was absent in the airways of homozygote mice as determined by immunofluorescence staining.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations