Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Tek-icre/ERT2)1Soff
MGI:3837451Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Tek-icre/ERT2)1Soff

Species
Mus musculus
Symbol
Tg(Tek-icre/ERT2)1Soff
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • tie2-CreERT2
Description
A tamoxifen-inducible icre recombinase gene and FRT-flanked beta-lactamase gene were inserted into the ATG start site of the murine Tek gene located on a BAC. After Flpe-mediated excision of the beta-lactamase gene, the targeted BAC was injected into FVB/N oocytes. Cre expression was detected in endothelial cells of numerous organs after treatment with tamoxifen.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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