Version: 8.0.0
Date: Tue Jan 28 2025
Eef1a1tm1(Kras*)Arge
MGI:3837679
Allele of Eef1a1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Eef1a1tm1(Kras*)Arge

Species
Mus musculus
Symbol
Eef1a1tm1(Kras*)Arge
Category
allele
Allele of gene
Eef1a1
Transgenic Constructs
Synonyms
  • Eef1a1-Kras*
Description
A loxP site flanked neomycin resistance gene and STOP cassette was inserted along with a constitutively active Kras with the amino acid substitution of glycine with aspartic acid at position 12 (p.G12D) into intron 1. Cre-mediated removal of the STOP cassette is required to achieve expression of the constitutively active Kras.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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