Allele/Variant

Tg(Cyp39a1-cre)7Aibs

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Cyp39a1-Tg7-cre

Description

The 206 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-370M9, containing the entire Cyp39a1 locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Cyp39a1 locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Cyp39a1 (Mmu)

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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