Allele/Variant

Mre11atm1Dof

Species
Mus musculus
Symbol
Mre11atm1Dof
Category
allele
Allele of gene
Mre11a
Transgenic Constructs
None
Synonyms
  • Mre11H129N
Description
Exon 5 was replaced with one in which a C to A substitution results in the amino acid substitution of histidine with asparagine at position 129 (p.H129N) in the encoded protein. This mutation occurs in nuclease motif III. A loxP site flanked neomycin resistance gene cassette was inserted into intron 5 and subsequently removed by transient cre expression in ES cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

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