Version: 8.0.0
Date: Tue Jan 28 2025
Pik3cgtm1Lste
MGI:3840088
Allele of Pik3cg
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Pik3cgtm1Lste

Species
Mus musculus
Symbol
Pik3cgtm1Lste
Category
allele
Allele of gene
Pik3cg
Transgenic Constructs
None
Synonyms
  • p110gammaDASAA
Description
Exon 2 was modified to encode 5 amino acid substitutions: T232D, K251A, K254S, K255A, K256A. This also creates an additional NheI restriction site. A floxed neomycin selection cassette was inserted in intron 1. The floxed neo was subsequently excised by crossing to Tg(CMV-cre)1Cgn. Western blot analysis indicates that expression is somewhat reduced and the protein is somewhat insensitive to RAS.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page