Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm1.1(CAG-lacZ,-EGFP)Glh
MGI:3840212
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm1.1(CAG-lacZ,-EGFP)Glh

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1.1(CAG-lacZ,-EGFP)Glh
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
None
Synonyms
  • R26NZG
  • R26ZG
Description
A vector containing a CAG promoter driving expression of a floxed neo/STOP cassette, frt flanked lacZ gene with 3 polyadenylation sequences (secondary STOP cassette) and a nuclear localization signal, and an EGFP gene was inserted into the locus. Germ line, cre mediated removal of the neo/STOP cassette allows for ubiquitous expression of the lacZ gene. The STOP cassette following the lacZ gene remains intact and prevents the expression of EGFP. Expression of EGFP requires flp mediated removal of the secondary STOP cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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