Allele/Variant

Bdnftm1Bail

Species
Mus musculus
Symbol
Bdnftm1Bail
Category
allele
Allele of gene
Bdnf
Transgenic Constructs
None
Synonyms
  • BDNF-KIV
  • KIV-
Description
An enhanced green fluorescent protein (EGFP)-STOP cassette, followed by a loxP-flanked neomycin selection cassette (neo) in reverse orientation was inserted 3' of the promoter IV exon. Promoter IV drives expression of a fusion transcript composed of GFP and the endogenous coding sequence. However, only a GFP protein is translated from this transcript because of the GFP stop codon. Kainic acid fails to induce the normal promoter IV transcript and fails to induce an increased production of the normal protein product.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page