Eif3f^{tm1(KOMP)Vlcg}

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Species

Mus musculus

Symbol

Eif3f^{tm1(KOMP)Vlcg}

Category

allele

Allele of gene

Eif3f

Transgenic Constructs

None

Synonyms

• eIF3f^-

Description

The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7130bp between positions 108533623-108540752 of Chromosome 7 (Build GRCm39). Real-time PCR and Western blot analyses revealed a ~50% reduction of mRNA and protein levels in all adult heterozygous tissues/organs examined. Quantification of immunoblots indicated that protein expression levels are decreased by 30-46% in adult heterozygous skeletal muscles.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations