Allele/Variant

Eif3ftm1(KOMP)Vlcg

Species
Mus musculus
Symbol
Eif3ftm1(KOMP)Vlcg
Category
allele
Allele of gene
Eif3f
Transgenic Constructs
None
Synonyms
  • eIF3f-
Description
The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7130bp between positions 108533623-108540752 of Chromosome 7 (Build GRCm39). Real-time PCR and Western blot analyses revealed a ~50% reduction of mRNA and protein levels in all adult heterozygous tissues/organs examined. Quantification of immunoblots indicated that protein expression levels are decreased by 30-46% in adult heterozygous skeletal muscles.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations