Allele/Variant

Tg(LRRK2)1Cjli

Species

Mus musculus

Symbol

Tg(LRRK2)1Cjli

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

BAC WT LRRK2
TG-WT-OX

Description

The human bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a 188 kb BAC containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene with 29 kb upstream of the LRRK2 start codon and 42 kb downstream of the LRRK2 stop codon. Bioinformatics analysis predicted that no other genes are present in the BAC. This BAC was microinjected into fertilized FVB/NTac zygotes.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

LRRK2 (Hsa)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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