Allele/Variant

Tg(TcraTcrbNY4.1)1Pesa

Species
Mus musculus
Symbol
Tg(TcraTcrbNY4.1)1Pesa
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • 4.1 NOD
  • 4.1-NOD
Description
Functional VDJ beta (V beta 11 and J beta 2.4) and VJ alpha (V alpha x4.1 and J alpha 33) rearrangements were isolated from the beta cell cytotoxic CD4(+) T cell clone NY4.1. Upstream regulatory sequences together with either TCR-beta or TCR-alpha enhancers, as appropriate, were associated with VDJbeta or VJalpha. The resulting TCR alpha and beta constructs were coinjected and cointegrated into (SJLXC57BL/6J)F2 oocytes.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations