Allele/Variant

Wif1tm1Dmth

Species
Mus musculus
Symbol
Wif1tm1Dmth
Category
allele
Allele of gene
Wif1
Transgenic Constructs
None
Synonyms
  • Wif1lacZ
Description
A tau-lacZ cassette and a floxed neo cassette were inserted into the initiation codon via homologous recombination. This insertion created multiple in-frame stop codons. In situ hybridization analysis indicates that lacZ expression recapitulates endogenous gene expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
increased incidence of induced tumors
MGI
increased osteosarcoma incidence
MGI
increased sarcoma incidence
MGI
increased susceptibility to induced morbidity/mortality
MGI
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Disease Associations

No data available