Allele/Variant

Mecomtm1Miku

Species
Mus musculus
Symbol
Mecomtm1Miku
Category
allele
Allele of gene
Mecom
Transgenic Constructs
None
Synonyms
  • Evi-1flox
  • Prdm3flox
Description
A loxP site was inserted upstream of exon 4 and a floxed neomycin cassette was placed downstream. After targeting and selection, transient expression of cre recombinase removed the neomycin cassette and left exon 4 floxed. Correct targeting was confirmed by Southern blotting. Expression of cre recombinase will remove exon 4, which encodes a zinc finger domain common to the three major protein isoforms of the gene locus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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