Allele/Variant

Mfngtm1Seco

Species
Mus musculus
Symbol
Mfngtm1Seco
Category
allele
Allele of gene
Mfng
Transgenic Constructs
None
Synonyms
  • Mfngdelta1
Description
An 898 bp fragment surrounding the first coding exon was replaced with a floxed neo cassette. Cre mediated recombination was then used to remove the floxed neo cassette. No phenotypic difference was reported between the neo in and neo out versions of this allele. Northern blot analysis detected the expression of an abnormal 2.0 kb RNA. RT-PCR and 5' RACE analysis indicate that this RNA includes exons 2-8 of the endogenous gene and a region from the first intron. Cell expression analysis indicates that the abnormal RNA would not produce a stable protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
no abnormal phenotype detectedMGI
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Disease Associations

No data available