Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Tg(Myh6-CYP2J2)#Dcz
- Species
- Mus musculus
- Symbol
- Tg(Myh6-CYP2J2)#Dcz
- Category
- allele
- Allele of gene
- None
- Transgenic Constructs
- None
- Synonyms
- None
- Description
- This transgene consists of human CYP2J2 cDNA cloned into a vector containing the mouse alpha-MHC promoter and human growth hormone intron and polyA sequence to drive cardiomyocyte-specific expression of the transgene. Six germline founder mice lines, Tr2, Tr3, Tr4, Tr5, Tr6, and Tr7 were generated. Of those 6 germline founders, 4 lines, Tr2, Tr3, Tr5, and Tr7 had abundant cardiac expression of the transgene. Heterozygous transgenic progeny of each of these four overexpressing lines were analyzed and data are presented as a pool of all four lines.
- Additional Information
- Literature