Allele/Variant

Tg(Myh6/tetO-PRKCA*)1Jmk

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

dnPrkca
Tg(dnPrkca)

Description

The rabbit PRKCA cDNA carrying the dominant negative L368A mutation was fused to the cardiac-specific alpha myosin heavy chain (Myh6) mouse promoter. The promoter is minimally active/attenuated through the ablation of three GATA sites and two thyroid-like response elements. Seven copies of tetracycline-responsive promoter element (tetO) are fused to the promoter.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

PRKCA

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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