Allele/Variant

Sox17tm1(icre)Heli

Species
Mus musculus
Symbol
Sox17tm1(icre)Heli
Category
allele
Allele of gene
Sox17
Transgenic Constructs
Synonyms
  • Sox17iCre
  • Sox17iCredeltaneo
Description
A targeting vector containing a mini gene locus with a codon improved cre recombinase cDNA with a translational stop codo, splice donor site, artificial intron and an exon encoding the SV40 polyadenylation signal followed by an FRT-flanked PGK-neo cassette in the opposite orientation was introduced into exon 1 of Sox17 by homologous recombination in TBV2 ES cells. Germline chimeras were generated and the neo cassette was excised by crossing these with Flpe mice.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
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