Allele/Variant

Ppm1bGt(AW0406)Wtsi

Species
Mus musculus
Symbol
Ppm1bGt(AW0406)Wtsi
Category
allele
Allele of gene
Ppm1b
Transgenic Constructs
None
Synonyms
  • Ppm1bd
Description
The lacZ and neomycin resistance genes containing gene trap vector inserted into intron 2 of the host gene. Transcrips from this allele will code for a fusion protein of the first 282 amino-acids of the host gene (which excludes the functional phosphatase domain), followed by beta-galactosidase and neo. Immunoblots show that a small amount of the wildtype L- and S-variants of the host gene peptides are still produced, possibly owing to splicing out of trap-containing intron 2.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations