Allele/Variant

Prss8Gt(IST10122F12)Tigm

Species
Mus musculus
Symbol
Prss8Gt(IST10122F12)Tigm
Category
allele
Allele of gene
Prss8
Transgenic Constructs
None
Synonyms
None
Description
Trapped gene association determined by genome coordinate overlap and strand. The retroviral gene trap vector inserted into intron 2. This insertion results in a null mutation by placing a strong splice acceptor site in intron 2, leading to formation of a truncated mRNA fused to a beta-geo reporter gene. RT-PCR confirmed absence of mRNA in the skin, intestine, kidneys and lungs and Western blot analysis confirmed absence of protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations