Allele/Variant

Sec23aGt(RRE297)Byg

Species
Mus musculus
Symbol
Sec23aGt(RRE297)Byg
Category
allele
Allele of gene
Sec23a
Transgenic Constructs
None
Synonyms
  • Sec23agt
Description
A gene trap vector inserted into intron 2. The resulting fusion transcript of the first two exons of the gene (encoding the first 73 amino acids) with the beta-geo cassette produces a chimeric protein missing over 90% of the coding region, which is expected to be nonfunctional. Western blot analysis using an antibody recognizing an internal epitope near the C-terminus confirmed the absence of protein expression in homozygous mutant embryonic fibroblast cell lysates.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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