Allele/Variant

Sh3glb2Gt(OST224737)Lex

Species
Mus musculus
Symbol
Sh3glb2Gt(OST224737)Lex
Category
allele
Allele of gene
Sh3glb2
Transgenic Constructs
None
Synonyms
  • B2KO
Description
A gene trap cassette inserted into intron 1 of the gene. The gene trap cassette includes a splice adaptor at the 5’ end with neomycin selection and poly(A) termination signals followed by another ES cell-only promotor that expresses the first exon of the Bruton’s tyrosine kinase gene with multiple termination codons to prevent expression of downstream fusion transcripts. Immunoblot analysis confirmed the absence of protein expression in isolated mouse embryonic fibroblasts (MEFs) and tissues from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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