Version: 8.0.0
Date: Tue Jan 28 2025
Grm5tm1.1Kksz
MGI:4353518
Allele of Grm5
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Grm5tm1.1Kksz

Species
Mus musculus
Symbol
Grm5tm1.1Kksz
Category
allele
Allele of gene
Grm5
Transgenic Constructs
None
Synonyms
  • Grm5R
  • mGluR5F1128R
Description
The open reading frame was replaced with one containing two point mutations (TTC to CGC) in exon 8. These mutations result in an amino acid substitution of arginine for phenylalanine at position 1128 (F1128R). An upstream floxed neo was removed by germ line, cre mediated recombination. This mutation is expected to reduce Homer binding.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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