Allele/Variant

Gt(ROSA)26Sor^{tm31(H1/tetO-RNAi:Insr)Arte}

Species: Mus musculus
Symbol: Gt(ROSA)26Sor^{tm31(H1/tetO-RNAi:Insr)Arte}
Category: allele
Allele of gene: Gt(ROSA)26Sor
Transgenic Constructs: None
Synonyms: None
Description: A short hairpin RNA directed against the insulin receptor (Insr) gene was targeted into the Rosa26 locus. The shRNA sequence is under the regulation of the tetO operator and a codon optimized tet repressor (itetR) under the control of a CAG promoter. The construct was transfected into Art B6-RMCE 68 ES cells derived from the C57BL/6 strain through Recombinase Mediated Cassette Exchange.
Additional Information: Literature

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Gt(ROSA)26Sortm31(H1/tetO-RNAi:Insr)Arte