Allele/Variant

Arxtm2Kki

Species
Mus musculus
Symbol
Arxtm2Kki
Category
allele
Allele of gene
Arx
Transgenic Constructs
None
Synonyms
  • ArxP355R
  • ArxPR
Description
Exon 2 was replaced with one in which nucleotide substitutions result in the amino acid substitution of proline with arginine at position 355 in the encoded protein (p.P355R), mimicking a mutation found in some X-linked lissencephaly patients. A neomycin resistance gene cassette was inserted into intron 2.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations