Allele/Variant

Sirt1tm3Fwa

Species
Mus musculus
Symbol
Sirt1tm3Fwa
Category
allele
Allele of gene
Sirt1
Transgenic Constructs
None
Synonyms
  • Sirt1-E4fl
  • SIRT1F
Description
A floxed neomycin resistance cassette in reverse orientation was placed at the 3' end of intron 3. An additional loxP site was inserted just downstream of exon 4. In the resulting ES cells, exon 4 is flanked by loxP sites. These mutant ES cells were used in the generation of Sirt1tm1Fwa mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations