Allele/Variant

Lpin120884

Species
Mus musculus
Symbol
Lpin120884
Category
allele
Allele of gene
Lpin1
Transgenic Constructs
None
Synonyms
None
Description
A T to A transversion is located in exon 20 resulting in a tyrosine to asparagine missense mutation (Y873N). Western blot analysis showed similar levels of protein expression in all tissues examined except adipose tissue where protein levels are about twice that of controls. In adipose tissue from homozygous mutant mice phosphatidate phosphatase type 1 activity is reduced to about 20% of controls.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations