Version: 8.0.0
Date: Tue Jan 28 2025
Bcl2l11tm3.1Boui
MGI:4366756
Allele of Bcl2l11
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Bcl2l11tm3.1Boui

Species
Mus musculus
Symbol
Bcl2l11tm3.1Boui
Category
allele
Allele of gene
Bcl2l11
Transgenic Constructs
None
Synonyms
  • BimP
  • BimPuma
Description
The BH3 domain (in exon 5) was replaced by the mouse Bbc3 (Puma) BH3 domain by site-directed mutagenesis using PCR. A loxP-PGKneo-loxP cassette was inserted 840 bp downstream of exon 5. The neo cassette was removed by crossing the mice to cre deleter transgenic mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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