Tg(tetO-HTR4*D100A)2Niss

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Species

Mus musculus

Symbol

Tg(tetO-HTR4*D100A)2Niss

Category

allele

Allele of gene

None

Transgenic Constructs

None

Synonyms

• TetO-Rs1

Description

The transgene vector was constructed to contain an aspartic acid to alanine amino acid residue change at position 100 making the gene product insensitive to serotonin. It is under the control of a TetO promoter. Three lines were established and designated as B (or 2), C, and G (or 7). This transgene was originally designated as line B (or 2). This line shows slightly less expression than line G.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations