Khk^tm2Dtb

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Species

Mus musculus

Symbol

Khk^tm2Dtb

Category

allele

Allele of gene

Khk

Transgenic Constructs

None

Synonyms

• KHK-A/C KO
• Khk^delta

Description

A stop codon was introduced into exon 3a preventing the production of the A transcript. A floxed neo cassette was inserted upstream of the modified exon 3a. Exons 4 through 6 and part of 7 were deleted, preventing the production of the C splice variant. Western blot analysis confirmed the absence of isoforms A and C.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations