Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Slc16a8-cre/ERT2,-EGFP)1Moss
MGI:4399744Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Slc16a8-cre/ERT2,-EGFP)1Moss

Species
Mus musculus
Symbol
Tg(Slc16a8-cre/ERT2,-EGFP)1Moss
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • RPECreER
Description
The transgene was constructed from a modification of BAC RP24-149-K18 such that a cassette containing an improved cre gene fused to the modified human ESR1 receptor (ERT2) and an IRES-EGFP followed by an frt-flanked neo cassette was inserted at the start of the Slc16a8 open reading frame. Transient flp expression in removed the neo cassette in bacterial cells. Cre activity is detected in the retinal pigment epithelium.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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