Version: 8.0.0
Date: Tue Jan 28 2025
Tg(CAG-CYP27A1)23Etl
MGI:4410298Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(CAG-CYP27A1)23Etl

Species
Mus musculus
Symbol
Tg(CAG-CYP27A1)23Etl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CYP27overexp
Description
The transgene construct has the human cytomegalovirus immediate early promoter enhancer with chicken beta-actin/rabbit beta-globin hybrid promoter (CAG; from the pCAGGS vector) driving expression of a 1.8 kb fragment encoding the human CYP27A1 (cytochrome P450, family 27, subfamily A, polypeptide 1) cDNA sequence. This transgene was microinjected into the pronuclei of fertilized mouse eggs taken from superovulated CBA females. The highest transgenic overexpressor founder mouse (23) was bred to wildtype C57BL/6J (Harlan) mice to establish line 23.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page