Allele/Variant

Tlr9m6Btlr

Species
Mus musculus
Symbol
Tlr9m6Btlr
Category
allele
Allele of gene
Tlr9
Transgenic Constructs
None
Synonyms
  • CpG7
  • Liesgen
Description
This mutation was discovered among G3 progeny of an ENU mutagenized mouse in a screen for susceptibility to induction of colitis by low doses of dextran sodium sulfate (DSS). The molecular change, in the second, last exon of the gene, results in a G to T transversion at nucleotide position 1944 of the mRNA that replaces the neutral arginine at amino acid position 648 with the polar leucine (R643L).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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