Version: 8.0.0
Date: Tue Jan 28 2025
Celsr1tm1.1Fati
MGI:4430218
Allele of Celsr1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Celsr1tm1.1Fati

Species
Mus musculus
Symbol
Celsr1tm1.1Fati
Category
allele
Allele of gene
Celsr1
Transgenic Constructs
None
Synonyms
None
Description
A loxP site and a neo cassette within intron 25 and an additional loxP site within intron 29 were added by homologous recombination. Cre-mediated recombination removed the floxed region. Translation of the mutant mRNA is predicted to produce a truncated protein with a scrambled sequence of 15 amino acids and a premature stop. Quantitative RT-PCR showed that transcript level was five fold lower in the mutant than in the wild-type.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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