Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky
MGI:4430527
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • P110*-transgene
  • R26Stop flox P110*
Description
The P110*-transgene is a targeting vector designed with (from 5' to 3') a splice acceptor site, a loxP-flanked Neo-STOP cassette, a cDNA sequence encoding P110* (a constituitively active form of mouse P110alpha [Pik3ca; the catalytic subunit of phosphatidylinositol 3-kinase]), an FRT-flanked internal ribosomal entry site-enhanced green fluorescent protein cassette (IRES-EGFP), and bovine polyadenylation signal. This transgene construct was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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