Allele/Variant

Nipsnap1tm1a(EUCOMM)Wtsi

Species
Mus musculus
Symbol
Nipsnap1tm1a(EUCOMM)Wtsi
Category
allele
Allele of gene
Nipsnap1
Transgenic Constructs
None
Synonyms
None
Description
The L1L2_gt2 cassette was inserted at position 4832877 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 4834363. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal locomotor activationMGI
increased mean corpuscular volumeMGI
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Disease Associations

No data available