Allele/Variant

Ctsztm1Thre

Species
Mus musculus
Symbol
Ctsztm1Thre
Category
allele
Allele of gene
Ctsz
Transgenic Constructs
None
Synonyms
  • Ctsz-
Description
Part of exon 2, which contains the active site cysteine critical for enzyme activity, and part of intron 3 were deleted by homologous recombination and replaced by a cassette comprising an independent ribosomal entry sequence (IRES), followed by a lacZ reporter gene and a neomycin cassette. Disruption of the gene was confirmed by RT-PCR and Western blot analyses.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations