Allele/Variant

Cryaatm1Ady

Species
Mus musculus
Symbol
Cryaatm1Ady
Category
allele
Allele of gene
Cryaa
Transgenic Constructs
None
Synonyms
  • CryaaR49Cneo
Description
The codon for arginine 49 was altered to cysteine by homologous recombination. A loxP flanked neomycin cassette was introduced between exon 1 and 2. The reduction in protein expression was confirmed by chromatography profile (30% in lens from heterozygous mice).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations