Allele/Variant

Stat3tm4Vpo

Species
Mus musculus
Symbol
Stat3tm4Vpo
Category
allele
Allele of gene
Stat3
Transgenic Constructs
None
Synonyms
  • Stat3C
Description
cDNA encoding the C-terminal portion of the gene with A661C and N663C mutations, as well as a polyA-neo cassette, was inserted into exon 20. The mutant protein was constitutively active and expressed at physiologic levels in mammary gland, liver and heart in both the homozygous and heterozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations