Dkkl1^tm1.1Mldp

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Species

Mus musculus

Symbol

Dkkl1^tm1.1Mldp

Category

allele

Allele of gene

Dkkl1

Transgenic Constructs

None

Synonyms

None

Description

A targeting vector was designed to insert loxP sites flanking exons 2-4 of the Dickkopf-Like 1 (Dkkl1) gene, and a frt-flanked neomycin resistance (neo) cassette upstream of the 3' loxP site. Cre mediated recombination removed exons 2 through 4 and the frt-flanked neo cassette. The absence of protein expression was confirmed by immunohistochemistry on testis samples.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations