Allele/Variant

Stk11tm1.1Sjm

Species
Mus musculus
Symbol
Stk11tm1.1Sjm
Category
allele
Allele of gene
Stk11
Transgenic Constructs
None
Synonyms
  • Lkb1fl
  • Stk11fl
Description
An FRT-flanked neo cassette with a 5'loxP site was inserted upstream of exon 3 and an additional loxP site was inserted downstream of exon 6. Flp mediated recombination removed the neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal bone marrow cell morphology/developmentMGI
abnormal bone marrow cell physiologyMGI
abnormal mitotic spindle morphologyMGI
aneuploidyMGI
decreased bone marrow cell numberMGI
decreased erythrocyte cell numberMGI
decreased hematopoietic stem cell numberMGI
decreased leukocyte cell numberMGI
increased hematopoietic stem cell numberMGI
increased mitochondrial fissionMGI
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Disease Associations

No data available