Version: 8.0.0
Date: Tue Jan 28 2025
Tie1tm1Scba
MGI:4441286
Allele of Tie1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tie1tm1Scba

Species
Mus musculus
Symbol
Tie1tm1Scba
Category
allele
Allele of gene
Tie1
Transgenic Constructs
None
Synonyms
  • Tie1neo
Description
A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 1. Western blot analysis confirmed a 76% reduction in protein expression in the lungs of E18.5 homozygous mice. This is a hypomorphic allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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