Allele/Variant

Pax3tm2Joe

Species
Mus musculus
Symbol
Pax3tm2Joe
Category
allele
Allele of gene
Pax3
Transgenic Constructs
None
Synonyms
  • Pax3NCE-neo
Description
A 674 bp neural crest enhancer region within the upstream genomic region was replaced by a flowed PGK-neo cassette. Immunohistochemistry showed a drastic reduction or complete loss of protein expression in homozygous embryos at E12.5. Removal of the PGK-neo cassette with Cre-expressing mice allows for tissue-specific rescue.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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