Allele/Variant

Irf7m1Btlr

Species
Mus musculus
Symbol
Irf7m1Btlr
Category
allele
Allele of gene
Irf7
Transgenic Constructs
None
Synonyms
  • inept
Description
The mutation comprises an A to G transition at nucleotide 749 of the mRNA sequence, in the fourth of the gene's 10 exons (Genbank record NM_016850; 148451039 bp on Chr 7, NCBI m37 mouse assembly (Build 37.1)). It results in replacement of aspartic acid by glycine at amino acid 110 (D110G), in the DNA-binding domain of the protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

NC_000073.7:g.140845053T>C

Symbol
NC_000073.7:g.140845053T>C
Category
Variant
Variant type
point mutation
Overlaps
Irf7
Location
7:140845053
Nucleotide Change
T>C
Most Severe Consequence
  • missense variant
See all consequences
HGVS.g name
  • 7:g.140845053T>C
  • NC_000073.7:g.140845053T>C
HGVS.c name
  • ENSEMBL:ENSMUST00000026571.1:c.329A>G
  • ENSEMBL:ENSMUST00000097952.1:c.329A>G
HGVS.p name
  • ENSEMBL:ENSMUSP00000026571:p.Asp110Gly
  • ENSEMBL:ENSMUSP00000095565:p.Asp110Gly
Synonyms
Not Available
Notes
Not Available
Cross references
MGI:4442855
References
All alleles with this variant

Genome location
Assembly version
GRCm39
Viewer Help
140.8435M140.8440M140.8445M140.8450M140.8455M140.8460M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.

Variant Molecular Consequences

Predicted effect of NC_000073.7:g.140845053T>C

Variant
NC_000073.7:g.140845053T>C
Variant type:
point_mutation
Sequence feature
Sequence feature type
Associated gene
Location
Molecular consequence
Codon and amino acid change
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    Phenotypes

    Disease Associations

    No data available