Allele/Variant

Irf7m1Btlr

Species
Mus musculus
Symbol
Irf7m1Btlr
Category
allele
Allele of gene
Irf7
Transgenic Constructs
None
Synonyms
  • inept
Description
The mutation comprises an A to G transition at nucleotide 749 of the mRNA sequence, in the fourth of the gene's 10 exons (Genbank record NM_016850; 148451039 bp on Chr 7, NCBI m37 mouse assembly (Build 37.1)). It results in replacement of aspartic acid by glycine at amino acid 110 (D110G), in the DNA-binding domain of the protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
decreased interferon-alpha secretionMGI
decreased interferon-beta secretionMGI
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Disease Associations

No data available