Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Gh1-cre)bKnmn
MGI:4442901Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Gh1-cre)bKnmn

Species
Mus musculus
Symbol
Tg(Gh1-cre)bKnmn
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • rGHp-Cre
Description
A 310 bp fragment 5' of the initiation codon of the rat growth hormone gene (Gh1) was used to drive cre recombinase in the construct. The purified construct was injected into FVB zygotes. Line b was determined (by Southern blot) to carry 3 copies of the insertion was established and analyzed in detail. RT-PCR results demonstrated high levels of cre mRNA expression in the pituitary, lower levels in the testis, and no expression in any other tissues. (Cre expression was also detected in cephalic extracts from animals at E17.)
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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