Version: 8.0.0
Date: Tue Jan 28 2025
Crhtm1(cre)Zjh
MGI:4452089
Allele of Crh
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Crhtm1(cre)Zjh

Species
Mus musculus
Symbol
Crhtm1(cre)Zjh
Category
allele
Allele of gene
Crh
Transgenic Constructs
Synonyms
  • CRF-iCre
  • CRF-ires-Cre
Description
A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the corticotropin releasing hormone locus (Crh). The mice were bred to actin-Flpe animals to remove the neo cassette and the Flpe transgene was subsequently bred out of the line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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