Allele/Variant

Mdktm1(KOMP)Mbp

Species
Mus musculus
Symbol
Mdktm1(KOMP)Mbp
Category
allele
Allele of gene
Mdk
Transgenic Constructs
None
Synonyms
None
Description
The insertion of the L1L2_Bact_P cassette created a deletion of size 697 starting at position 91761104 and ending at position 91761801 of Chromosome 2 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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