Allele/Variant

Lmnatm5Lgf

Species
Mus musculus
Symbol
Lmnatm5Lgf
Category
allele
Allele of gene
Lmna
Transgenic Constructs
None
Synonyms
  • LmnanPLAO
Description
Introns 10 and 11 of Lmna were deleted thereby abolishing production of lamin C and producing a only non-farnesylated prelamin A. A point mutation was introduced into exon 12 that changes the cysteine of prelamin A's CaaX motif to a serine (i.e. CSIM to SSIM).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations