Allele/Variant

Tg(LRRK2)WT1Mjfa

Species
Mus musculus
Symbol
Tg(LRRK2)WT1Mjfa
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • hWT
  • LRRK2 WT
Description
These transgenic mice express the human LRRK2 gene with high levels of protein detected, with an expression pattern similar to that of endogenous mouse Lrrk2. The transgene inserted into Chromosome 12. Transgenic mice express human LRRK2 approximately 20-22 fold over the endogenous mouse Lrrk2 level. Line WT1 was generated.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations