Bmp4^tm5.1Bhr

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Species

Mus musculus

Symbol

Bmp4^tm5.1Bhr

Category

allele

Allele of gene

Bmp4

Transgenic Constructs

None

Synonyms

• Bmp4^CFP

Description

A floxed Pgk-neo-bpA cassette was inserted into the Eco RI site into the preserved third intron in reverse orientation. An improved YFP, Citrine, coding sequence was inserted into the fourth exon as an in-frame fusion after the furin cleavage site that generates the mature peptide. The floxed Neo cassette was removed through crossing with Sox2-Cre transgenic animals. Although no endogenous sequence was deleted, this allele was determined to be functionally null allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations