Version: 8.0.0
Date: Tue Jan 28 2025
Tg(CAG-Map3k7*K63W)1232Mds
MGI:4461396Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(CAG-Map3k7*K63W)1232Mds

Species
Mus musculus
Symbol
Tg(CAG-Map3k7*K63W)1232Mds
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CAG-CATlox-TAK1K63W
  • stop-dnTAK
Description
This transgene consists of the chicken beta-actin promoter followed by a loxP flanked stop, a kinase-inactive Map3k7 with a K63W mutation, and a polyadenylation signal. Cre mediated recombination removes the stop and allows expression of the kinase-inactive Map3k7 gene. Map3k7 expression is increased about 4 fold and this is the highest expressing line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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